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Wednesday, March 5, 2014

Peregrine Pharmaceuticals (PPHM) pops to $2.82

Earnings in two days and then below:

Maybe now it will soar. (That's the Peregrine Falcon, the fastest moving creature on earth--Its here for a reason! It's only the first day up!)

PRESENTATION DETAILS:
CONFERENCE: IMMUNE EVOLUTION IN CANCER Plenary Talk: Phosphatidylserine-Targeting Antibodies Induce M1 Macrophage Polarization, Promote Myeloid Derived Suppressor Cell Differentiation and Boost Tumor-Specific Immunity
Presenter: Xianming Huang, Ph.D., Assistant Professor, Hamon Center for Therapeutic Oncology, Pharmacology, Simmons Comprehensive Cancer Center University of Texas Southwestern Medical Center, Dallas, Texas
Date: Wednesday, March 12, 2014
Time: 2:30 P.M. - 4:30 P.M. Pacific Time
Workshop: #3: Immune Suppressive Myeloid Cells
Location: MacDonald DEF Room, Fairmont Chateau Whistler, Whistler, British Columbia, Canada


CONFERENCE: IMMUNE EVOLUTION IN CANCERTitle: Phosphatidylserine Targeting Antibodies Enhance the Activity of Immune Checkpoint Inhibitors in Tumors
Presenter: Bruce Freimark, Ph.D., Director of Pre-Clinical Research Oncology, Peregrine Pharmaceuticals
Poster: Poster Session 1 - Poster 1029
Date: Monday, March 10, 2014
Viewing: 1:00 P.M. - 10:00 P.M. Pacific Time
Presentation: 7:30 P.M. - 10:00 P.M. Pacific Time
Location: Frontenac Ballroom and Foyer - Fairmont Chateau Whistler, Whistler, British Columbia, Canada
CONFERENCE: HIV PATHOGENESIS VIRUS VERSUS HOST Title: Phosphatidylserine-Targeting Antibody Triggers B-Chemokine Release from Monocytes by Cell-Cell Crosslinking and is a Potent Inhibitor of HIV-1 In Vitro
Presenter: Cyril Empig, Ph.D., Associate Director, Pre-Clinical Research Infectious Disease, Peregrine Pharmaceuticals
Poster: Poster Session 3 - Poster 3020
Date: Wednesday, March 12, 2014
Viewing: 1:00 P.M. - 10:00 P.M. Mountain Time
Presentation: 7:30 P.M. - 10:00 P.M. Mountain Time
Location: Mezzanine 2 - Fairmont Banff Springs, Alberta, Canada
About Bavituximab: A Targeted ImmunotherapyBavituximab is a first-in-class phosphatidylserine (PS)-targeting monoclonal antibody that represents a new approach to treating cancer. PS is a highly immunosuppressive molecule usually located inside the membrane of healthy cells, but "flips" and becomes exposed on the outside of cells that line tumor blood vessels, creating a specific target for anti-cancer treatments. PS-targeting antibodies target and bind to PS and block this immunosuppressive signal, thereby enabling the immune system to recognize and fight the tumor. These data detailing the immune-stimulatory mechanism of action of PS-targeting antibodies, such as the company's lead drug candidate bavituximab, are the subject of a manuscript published in the October 2013 issue of the American Association for Cancer Research (AACR) peer-reviewed journal, Cancer Immunology Research. Bavituximab is currently being evaluated in several solid tumor indications, including non-small cell lung cancer, breast cancer, liver cancer and rectal cancer with a trial in advanced melanoma anticipated to initiate in the near future.

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